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the frontline 14 ISE Magazine | www.iise.org/ISEmagazine the front line © 2016 Scott Adams. Used by permission of Andrews McMeel Syndication. All rights reserved. Dilbert Cornell researchers have created a microscale artificial small intestine that researchers can use to develop thera- pies and gain insights into the evolution of human biol- ogy. Since the artificial intestine is 3-D printed, almost any research group can make one and tailor such systems to its specific needs, according to the university. The model mimics gut surface topography (texture and structure) and fluid flow that epithelial (gut surface) cells require to grow, reproduce and function properly. Other artificial intestines have failed to model peristaltic fluid flow. The paper, "Microscale bioreactors for in situ charac- terization of GI epithelial cell physiology," was published Oct. 2 in Scie tific Reports. Co-authors include researchers at Johns Hopkins University, the National University of Singapore and the University of Maryland. Gut-check in 3-D Artificial small intestine could lead to new therapies Cornell researchers have developed an artificial 3-D small intestine. The image on the left shows cells dying off (light blue) along the tips of intestinal villi, a response to fluid flow in the intestine that mimics living guts. The frame on the right shows that when such flow is missing, cells all along villi become self-destroying (as seen by light blue and green areas). Photo courtesy Cait M. Costello | Cornell University Corporate social responsibility cuts both ways "If a CEO has invested in CSR [corporate social responsibility] and the firm performs poorly, [he or she is] much more likely to be dismissed. On the other hand, if they have invested in CSR and the firm performs well, they are less likely to be fired. This shows that CSR investments can be a double-edged sword – do well and they'll buffer you from dismissal, do poorly and you're more likely [to] lose your job." — Tim Hubbard, a Notre Dame assistant professor of management, on his team's research in Strategic Management Journal on how company investments in corporate social responsibility affect the fate of CEOs. Quote, unquote